C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver

The unfolded protein response (UPR) senses stress in the endoplasmic reticulum (ER) and initiates signal transduction cascades that culminate in changes to gene regulation. Long recognized as a means for improving ER protein folding through up-regulation of ER chaperones, the UPR is increasingly rec...

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Hlavní autoři: Chikka, Madhusudana R., McCabe, Diane DeZwaan, Tyra, Heather M., Rutkowski, D. Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567690/
https://ncbi.nlm.nih.gov/pubmed/23281479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432344
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