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C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver

The unfolded protein response (UPR) senses stress in the endoplasmic reticulum (ER) and initiates signal transduction cascades that culminate in changes to gene regulation. Long recognized as a means for improving ER protein folding through up-regulation of ER chaperones, the UPR is increasingly rec...

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Bibliografske podrobnosti
Main Authors: Chikka, Madhusudana R., McCabe, Diane DeZwaan, Tyra, Heather M., Rutkowski, D. Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567690/
https://ncbi.nlm.nih.gov/pubmed/23281479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432344
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