Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin

Por Hidaka, Koushi, Kimura, Tooru, Ruben, Adam J., Uemura, Tsuyoshi, Kamiya, Mami, Kiso, Aiko, Okamoto, Tetsuya, Tsuchiya, Yumi, Hayashi, Yoshio, Freire, Ernesto, Kiso, Yoshiaki
Publicado no Bioorg Med Chem (2008)

Protection against Plasmodium falciparum malaria by PfSPZ Vaccine

Por Epstein, Judith E., Paolino, Kristopher M., Richie, Thomas L., Sedegah, Martha, Singer, Alexandra, Ruben, Adam J., Chakravarty, Sumana, Stafford, April, Ruck, Richard C., Eappen, Abraham G., Li, Tao, Billingsley, Peter F., Manoj, Anita, Silva, Joana C., Moser, Kara, Nielsen, Robin, Tosh, Donna, Cicatelli, Susan, Ganeshan, Harini, Case, Jessica, Padilla, Debbie, Davidson, Silas, Garver, Lindsey, Saverino, Elizabeth, Murshedkar, Tooba, Gunasekera, Anusha, Twomey, Patrick S., Reyes, Sharina, Moon, James E., James, Eric R., KC, Natasha, Li, Minglin, Abot, Esteban, Belmonte, Arnel, Hauns, Kevin, Belmonte, Maria, Huang, Jun, Vasquez, Carlos, Remich, Shon, Carrington, Mary, Abebe, Yonas, Tillman, Amy, Hickey, Bradley, Regules, Jason, Villasante, Eileen, Sim, B. Kim Lee, Hoffman, Stephen L.
Publicado no JCI Insight (2017)

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

Por Lyke, Kirsten E., Ishizuka, Andrew S., Berry, Andrea A., Chakravarty, Sumana, DeZure, Adam, Enama, Mary E., James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Manoj, Anita, Li, Minglin, Ruben, Adam J., Li, Tao, Eappen, Abraham G., Stafford, Richard E., KC, Natasha, Murshedkar, Tooba, Mendoza, Floreliz H., Gordon, Ingelise J., Zephir, Kathryn L., Holman, LaSonji A., Plummer, Sarah H., Hendel, Cynthia S., Novik, Laura, Costner, Pamela J. M., Saunders, Jamie G., Berkowitz, Nina M., Flynn, Barbara J., Nason, Martha C., Garver, Lindsay S., Laurens, Matthew B., Plowe, Christopher V., Richie, Thomas L., Graham, Barney S., Roederer, Mario, Sim, B. Kim Lee, Ledgerwood, Julie E., Hoffman, Stephen L., Seder, Robert A.
Publicado no Proc Natl Acad Sci U S A (2017)