Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin

le Hidaka, Koushi, Kimura, Tooru, Ruben, Adam J., Uemura, Tsuyoshi, Kamiya, Mami, Kiso, Aiko, Okamoto, Tetsuya, Tsuchiya, Yumi, Hayashi, Yoshio, Freire, Ernesto, Kiso, Yoshiaki
Foilsithe in Bioorg Med Chem (2008)

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

le Lell, Bertrand, Mordmüller, Benjamin, Dejon Agobe, Jean-Claude, Honkpehedji, Josiane, Zinsou, Jeannot, Mengue, Juliana Boex, Loembe, Marguerite Massinga, Adegnika, Ayola Akim, Held, Jana, Lalremruata, Albert, Nguyen, The Trong, Esen, Meral, KC, Natasha, Ruben, Adam J., Chakravarty, Sumana, Lee Sim, B. Kim, Billingsley, Peter F., James, Eric R., Richie, Thomas L., Hoffman, Stephen L., Kremsner, Peter G.
Foilsithe in Am J Trop Med Hyg (2018)

Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults

le Jongo, Said A., Shekalaghe, Seif A., Church, L. W. Preston, Ruben, Adam J., Schindler, Tobias, Zenklusen, Isabelle, Rutishauser, Tobias, Rothen, Julian, Tumbo, Anneth, Mkindi, Catherine, Mpina, Maximillian, Mtoro, Ali T., Ishizuka, Andrew S., Kassim, Kamaka Ramadhani, Milando, Florence A., Qassim, Munira, Juma, Omar A., Mwakasungula, Solomon, Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Chakravarty, Sumana, Saverino, Elizabeth, Bakari, Bakari M., Billingsley, Peter F., Seder, Robert A., Daubenberger, Claudia, Sim, B. Kim Lee, Richie, Thomas L., Tanner, Marcel, Abdulla, Salim, Hoffman, Stephen L.
Foilsithe in Am J Trop Med Hyg (2018)

Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults

le Jongo, Said A, Church, L W Preston, Mtoro, Ali T, Schindler, Tobias, Chakravarty, Sumana, Ruben, Adam J, Swanson, Phillip A, Kassim, Kamaka R, Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A, Qassim, Munira, Juma, Omar A, Bakari, Bakari M, Simon, Beatus, James, Eric R, Abebe, Yonas, KC, Natasha, Saverino, Elizabeth, Fink, Martina, Cosi, Glenda, Gondwe, Linda, Studer, Fabian, Styers, David, Seder, Robert A, Schindler, Tobias, Billingsley, Peter F, Daubenberger, Claudia, Sim, B Kim Lee, Tanner, Marcel, Richie, Thomas L, Abdulla, Salim, Hoffman, Stephen L
Foilsithe in Clin Infect Dis (2019)

Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity...

le Olotu, Ally, Urbano, Vicente, Hamad, Ali, Eka, Martin, Chemba, Mwajuma, Nyakarungu, Elizabeth, Raso, Jose, Eburi, Esther, Mandumbi, Dolores O., Hergott, Dianna, Maas, Carl D., Ayekaba, Mitoha O., Milang, Diosdado N., Rivas, Matilde R., Schindler, Tobias, Embon, Oscar M., Ruben, Adam J., Saverino, Elizabeth, Abebe, Yonas, KC, Natasha, James, Eric R., Murshedkar, Tooba, Manoj, Anita, Chakravarty, Sumana, Li, Minglin, Adams, Matthew, Schwabe, Christopher, Segura, J. Luis, Daubenberger, Claudia, Tanner, Marcel, Richie, Thomas L., Billingsley, Peter F., Lee Sim, B. Kim, Abdulla, Salim, Hoffman, Stephen L.
Foilsithe in Am J Trop Med Hyg (2018)

Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and...

le Jongo, Said A., Church, L. W. Preston, Mtoro, Ali T., Chakravarty, Sumana, Ruben, Adam J., Swanson, Phillip A., Kassim, Kamaka R., Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A., Qassim, Munira, Juma, Omar A., Bakari, Bakari M., Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Saverino, Elizabeth, Gondwe, Linda, Studer, Fabian, Fink, Martina, Cosi, Glenda, El-Khorazaty, Jill, Styers, David, Seder, Robert A., Schindler, Tobias, Billingsley, Peter F., Daubenberger, Claudia, Sim, B. Kim Lee, Tanner, Marcel, Richie, Thomas L., Abdulla, Salim, Hoffman, Stephen L.
Foilsithe in Am J Trop Med Hyg (2019)

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial

le Sissoko, Mahamadou S, Healy, Sara A, Katile, Abdoulaye, Omaswa, Freda, Zaidi, Irfan, Gabriel, Erin E, Kamate, Bourama, Samake, Yacouba, Guindo, Merepen A, Dolo, Amagana, Niangaly, Amadou, Niaré, Karamoko, Zeguime, Amatigue, Sissoko, Kourane, Diallo, Hama, Thera, Ismaila, Ding, Kelly, Fay, Michael P, O’Connell, Elise M, Nutman, Thomas B, Wong-Madden, Sharon, Murshedkar, Tooba, Ruben, Adam J, Li, Minglin, Abebe, Yonas, Manoj, Anita, Gunasekera, Anusha, Chakravarty, Sumana, Sim, B Kim Lee, Billingsley, Peter F, James, Eric R, Walther, Michael, Richie, Thomas L, Hoffman, Stephen L, Doumbo, Ogobara, Duffy, Patrick E
Foilsithe in Lancet Infect Dis (2017)

Protection against Plasmodium falciparum malaria by PfSPZ Vaccine

le Epstein, Judith E., Paolino, Kristopher M., Richie, Thomas L., Sedegah, Martha, Singer, Alexandra, Ruben, Adam J., Chakravarty, Sumana, Stafford, April, Ruck, Richard C., Eappen, Abraham G., Li, Tao, Billingsley, Peter F., Manoj, Anita, Silva, Joana C., Moser, Kara, Nielsen, Robin, Tosh, Donna, Cicatelli, Susan, Ganeshan, Harini, Case, Jessica, Padilla, Debbie, Davidson, Silas, Garver, Lindsey, Saverino, Elizabeth, Murshedkar, Tooba, Gunasekera, Anusha, Twomey, Patrick S., Reyes, Sharina, Moon, James E., James, Eric R., KC, Natasha, Li, Minglin, Abot, Esteban, Belmonte, Arnel, Hauns, Kevin, Belmonte, Maria, Huang, Jun, Vasquez, Carlos, Remich, Shon, Carrington, Mary, Abebe, Yonas, Tillman, Amy, Hickey, Bradley, Regules, Jason, Villasante, Eileen, Sim, B. Kim Lee, Hoffman, Stephen L.
Foilsithe in JCI Insight (2017)

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

le Lyke, Kirsten E., Ishizuka, Andrew S., Berry, Andrea A., Chakravarty, Sumana, DeZure, Adam, Enama, Mary E., James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Manoj, Anita, Li, Minglin, Ruben, Adam J., Li, Tao, Eappen, Abraham G., Stafford, Richard E., KC, Natasha, Murshedkar, Tooba, Mendoza, Floreliz H., Gordon, Ingelise J., Zephir, Kathryn L., Holman, LaSonji A., Plummer, Sarah H., Hendel, Cynthia S., Novik, Laura, Costner, Pamela J. M., Saunders, Jamie G., Berkowitz, Nina M., Flynn, Barbara J., Nason, Martha C., Garver, Lindsay S., Laurens, Matthew B., Plowe, Christopher V., Richie, Thomas L., Graham, Barney S., Roederer, Mario, Sim, B. Kim Lee, Ledgerwood, Julie E., Hoffman, Stephen L., Seder, Robert A.
Foilsithe in Proc Natl Acad Sci U S A (2017)