Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults

BACKGROUND: A vaccine would be an ideal tool for reducing malaria’s impact. PfSPZ Vaccine (radiation attenuated, aseptic, purified, cryopreserved Plasmodium falciparum [Pf] sporozoites [SPZ]) has been well tolerated and safe in >1526 malaria-naive and experienced 6-month to 65-year-olds in the Un...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Jongo, Said A, Church, L W Preston, Mtoro, Ali T, Schindler, Tobias, Chakravarty, Sumana, Ruben, Adam J, Swanson, Phillip A, Kassim, Kamaka R, Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A, Qassim, Munira, Juma, Omar A, Bakari, Bakari M, Simon, Beatus, James, Eric R, Abebe, Yonas, KC, Natasha, Saverino, Elizabeth, Fink, Martina, Cosi, Glenda, Gondwe, Linda, Studer, Fabian, Styers, David, Seder, Robert A, Billingsley, Peter F, Daubenberger, Claudia, Sim, B Kim Lee, Tanner, Marcel, Richie, Thomas L, Abdulla, Salim, Hoffman, Stephen L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947995/
https://ncbi.nlm.nih.gov/pubmed/31782768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz1152
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