Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

Controlled human malaria infection (CHMI) by direct venous inoculation (DVI) with 3,200 cryopreserved Plasmodium falciparum sporozoites (PfSPZ) consistently leads to parasitemia and malaria symptoms in malaria-naive adults. We used CHMI by DVI to investigate infection rates, parasite kinetics, and m...

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Publicado no:Am J Trop Med Hyg
Main Authors: Lell, Bertrand, Mordmüller, Benjamin, Dejon Agobe, Jean-Claude, Honkpehedji, Josiane, Zinsou, Jeannot, Mengue, Juliana Boex, Loembe, Marguerite Massinga, Adegnika, Ayola Akim, Held, Jana, Lalremruata, Albert, Nguyen, The Trong, Esen, Meral, KC, Natasha, Ruben, Adam J., Chakravarty, Sumana, Lee Sim, B. Kim, Billingsley, Peter F., James, Eric R., Richie, Thomas L., Hoffman, Stephen L., Kremsner, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929186/
https://ncbi.nlm.nih.gov/pubmed/29260650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.17-0343
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