Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults

We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce time and costs of developing PfSPZ Vaccine to prevent malaria in Africa. Immunization with five doses...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Jongo, Said A., Shekalaghe, Seif A., Church, L. W. Preston, Ruben, Adam J., Schindler, Tobias, Zenklusen, Isabelle, Rutishauser, Tobias, Rothen, Julian, Tumbo, Anneth, Mkindi, Catherine, Mpina, Maximillian, Mtoro, Ali T., Ishizuka, Andrew S., Kassim, Kamaka Ramadhani, Milando, Florence A., Qassim, Munira, Juma, Omar A., Mwakasungula, Solomon, Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Chakravarty, Sumana, Saverino, Elizabeth, Bakari, Bakari M., Billingsley, Peter F., Seder, Robert A., Daubenberger, Claudia, Sim, B. Kim Lee, Richie, Thomas L., Tanner, Marcel, Abdulla, Salim, Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090339/
https://ncbi.nlm.nih.gov/pubmed/29943719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.17-1014
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