Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults

We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce time and costs of developing PfSPZ Vaccine to prevent malaria in Africa. Immunization with five doses...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Trop Med Hyg
Main Authors: Jongo, Said A., Shekalaghe, Seif A., Church, L. W. Preston, Ruben, Adam J., Schindler, Tobias, Zenklusen, Isabelle, Rutishauser, Tobias, Rothen, Julian, Tumbo, Anneth, Mkindi, Catherine, Mpina, Maximillian, Mtoro, Ali T., Ishizuka, Andrew S., Kassim, Kamaka Ramadhani, Milando, Florence A., Qassim, Munira, Juma, Omar A., Mwakasungula, Solomon, Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Chakravarty, Sumana, Saverino, Elizabeth, Bakari, Bakari M., Billingsley, Peter F., Seder, Robert A., Daubenberger, Claudia, Sim, B. Kim Lee, Richie, Thomas L., Tanner, Marcel, Abdulla, Salim, Hoffman, Stephen L.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society of Tropical Medicine and Hygiene 2018
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090339/
https://ncbi.nlm.nih.gov/pubmed/29943719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.17-1014
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