The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients: study protocol for a randomized controlled trial

por Rowlands, Martin, Forward, Daren P, Sahota, Opinder, Moppett, Iain K
Publicado 2013

Femoral nerve block Intervention in Neck of Femur fracture (FINOF): study protocol for a randomized controlled trial

por Sahota, Opinder, Rowlands, Martin, Bradley, Jim, Van de Walt, Gerrie, Bedforth, Nigel, Armstrong, Sarah, Moppett, Iain
Publicado 2014

Pre-Operative nutrition In Neck of femur Trial (POINT) - carbohydrate loading in patients with fragility hip fracture: study protocol for a randomised controlled trial

por Moppett, Iain K, Greenhaff, Paul L, Ollivere, Ben J, Joachim, Theophillus, Lobo, Dileep N, Rowlands, Martin
Publicado en Trials (2014)

Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomised controlled trial

por Rowlands, Martin, van de Walt, Gerrie, Bradley, Jim, Mannings, Alexa, Armstrong, Sarah, Bedforth, Nigel, Moppett, Iain K, Sahota, Opinder
Publicado en BMJ Open (2018)

Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70

por Cheeseman, Matthew D., Westwood, Isaac M., Barbeau, Olivier, Rowlands, Martin, Dobson, Sarah, Jones, Alan M., Jeganathan, Fiona, Burke, Rosemary, Kadi, Nadia, Workman, Paul, Collins, Ian, van Montfort, Rob L. M., Jones, Keith
Publicado en J Med Chem (2016)

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

por Ali, Maruf M U, Bagratuni, Tina, Davenport, Emma L, Nowak, Piotr R, Silva-Santisteban, M Cris, Hardcastle, Anthea, McAndrews, Craig, Rowlands, Martin G, Morgan, Gareth J, Aherne, Wynne, Collins, Ian, Davies, Faith E, Pearl, Laurence H
Publicado 2011

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)

por Chessum, Nicola E. A., Sharp, Swee Y., Caldwell, John J., Pasqua, A. Elisa, Wilding, Birgit, Colombano, Giampiero, Collins, Ian, Ozer, Bugra, Richards, Meirion, Rowlands, Martin, Stubbs, Mark, Burke, Rosemary, McAndrew, P. Craig, Clarke, Paul A., Workman, Paul, Cheeseman, Matthew D., Jones, Keith
Publicado en J Med Chem (2017)

Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

por McHardy, Tatiana, Caldwell, John J., Cheung, Kwai-Ming, Hunter, Lisa J., Taylor, Kevin, Rowlands, Martin, Ruddle, Ruth, Henley, Alan, de Haven Brandon, Alexis, Valenti, Melanie, Davies, Thomas G., Fazal, Lynsey, Seavers, Lisa, Raynaud, Florence I., Eccles, Suzanne A., Aherne, G. Wynne, Garrett, Michelle D., Collins, Ian
Publicado 2010

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

por Jones, Alan M., Westwood, Isaac M., Osborne, James D., Matthews, Thomas P., Cheeseman, Matthew D., Rowlands, Martin G., Jeganathan, Fiona, Burke, Rosemary, Lee, Diane, Kadi, Nadia, Liu, Manjuan, Richards, Meirion, McAndrew, Craig, Yahya, Norhakim, Dobson, Sarah E., Jones, Keith, Workman, Paul, Collins, Ian, van Montfort, Rob L. M.
Publicado en Sci Rep (2016)

Privileged Structures and Polypharmacology within and between Protein Families

por Meyers, Joshua, Chessum, Nicola E. A., Ali, Salyha, Mok, N. Yi, Wilding, Birgit, Pasqua, A. Elisa, Rowlands, Martin, Tucker, Michael J., Evans, Lindsay E., Rye, Carl S., O’Fee, Lisa, Le Bihan, Yann-Vaï, Burke, Rosemary, Carter, Michael, Workman, Paul, Blagg, Julian, Brown, Nathan, van Montfort, Rob L. M., Jones, Keith, Cheeseman, Matthew D.
Publicado en ACS Med Chem Lett (2018)

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

por Cheeseman, Matthew D., Chessum, Nicola E. A., Rye, Carl S., Pasqua, A. Elisa, Tucker, Michael J., Wilding, Birgit, Evans, Lindsay E., Lepri, Susan, Richards, Meirion, Sharp, Swee Y., Ali, Salyha, Rowlands, Martin, O’Fee, Lisa, Miah, Asadh, Hayes, Angela, Henley, Alan T., Powers, Marissa, te Poele, Robert, De Billy, Emmanuel, Pellegrino, Loredana, Raynaud, Florence, Burke, Rosemary, van Montfort, Rob L. M., Eccles, Suzanne A., Workman, Paul, Jones, Keith
Publicado en J Med Chem (2016)