Genetics of idiopathic inflammatory myopathies: insights into disease pathogenesis

著者: Rothwell, Simon, Chinoy, Hector, Lamb, Janine A.
出版年 Curr Opin Rheumatol (2019)

Genetics in inclusion body myositis

著者: Rothwell, Simon, Lilleker, James B., Lamb, Janine A.
出版年 Curr Opin Rheumatol (2017)

The Ca(V)β Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel Ca(V)2.2 from Proteasomal Degradation but Not Oligoubiquitination

著者: Page, Karen M., Rothwell, Simon W., Dolphin, Annette C.
出版年 J Biol Chem (2016)

Strategies for Evaluating Idiopathic Inflammatory Myopathy Disease Susceptibility Genes

著者: Rothwell, Simon, Cooper, Robert G., Lamb, Janine A., Chinoy, Hector
出版年 Curr Rheumatol Rep (2014)

Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis

著者: Parkes, Joanna E., Rothwell, Simon, Oldroyd, Alexander, Chinoy, Hector, Lamb, Janine A.
出版年 Arthritis Res Ther (2018)

Direct Gating of ATP-activated Ion Channels (P2X2 Receptors) by Lipophilic Attachment at the Outer End of the Second Transmembrane Domain

著者: Rothwell, Simon W., Stansfeld, Phillip J., Bragg, Laricia, Verkhratsky, Alexej, North, R. Alan
出版事項 2014

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α(2)δ-1 subunit

著者: Kadurin, Ivan, Rothwell, Simon W., Lana, Beatrice, Nieto-Rostro, Manuela, Dolphin, Annette C.
出版年 Sci Rep (2017)

P2X(7)R activation drives distinct IL-1 responses in dendritic cells compared to macrophages

著者: Englezou, Pavlos C., Rothwell, Simon W., Ainscough, Joseph S., Brough, David, Landsiedel, Robert, Verkhratsky, Alexei, Kimber, Ian, Dearman, Rebecca J.
出版年 Cytokine (2015)

Searching for “monogenic diabetes” in dogs using a candidate gene approach

著者: Short, Andrea D, Holder, Angela, Rothwell, Simon, Massey, Jonathan, Scholey, Rachel, Kennedy, Lorna J, Catchpole, Brian, Ollier, William ER
出版年 Canine Genet Epidemiol (2014)

Association of an MHC Class II Haplotype with Increased Risk of Polymyositis in Hungarian Vizsla Dogs

著者: Massey, Jonathan, Rothwell, Simon, Rusbridge, Clare, Tauro, Anna, Addicott, Diane, Chinoy, Hector, Cooper, Robert G., Ollier, William E. R., Kennedy, Lorna J.
出版事項 2013

Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies

著者: Parkes, Joanna E., Rothwell, Simon, Day, Philip J., McHugh, Neil J., Betteridge, Zoë E., Cooper, Robert G., Ollier, William E., Chinoy, Hector, Lamb, Janine A.
出版年 Arthritis Res Ther (2016)

Proteolytic maturation of α(2)δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels

著者: Kadurin, Ivan, Ferron, Laurent, Rothwell, Simon W, Meyer, James O, Douglas, Leon R, Bauer, Claudia S, Lana, Beatrice, Margas, Wojciech, Alexopoulos, Orpheas, Nieto-Rostro, Manuela, Pratt, Wendy S, Dolphin, Annette C
出版年 eLife (2016)

Disruption of the Key Ca(2+) Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking

著者: Meyer, James O., Dahimene, Shehrazade, Page, Karen M., Ferron, Laurent, Kadurin, Ivan, Ellaway, Joseph I.J., Zhao, Pengxiang, Patel, Tarun, Rothwell, Simon W., Lin, Peipeng, Pratt, Wendy S., Dolphin, Annette C.
出版年 Cell Rep (2019)

The myositis clinical phenotype associated with anti-Zo autoantibodies: a case series of nine UK patients

著者: Tansley, Sarah L, Betteridge, Zoe, Lu, Hui, Davies, Emma, Rothwell, Simon, New, Paul P, Chinoy, Hector, Gordon, Patrick, Gunawardena, Harsha, Lloyd, Mark, Stratton, Richard, Cooper, Robert, McHugh, Neil J
出版年 Rheumatology (Oxford) (2020)

Dense Genotyping of Immune-Related Loci in the Idiopathic Inflammatory Myopathies Confirms HLA alleles as Strongest Genetic Risk Factor and Suggests Different Genetic Background fo...

著者: Rothwell, Simon, Cooper, Robert G., Lundberg, Ingrid E., Miller, Frederick W., Gregersen, Peter K., Bowes, John, Vencovsky, Jiri, Danko, Katalin, Limaye, Vidya, Selva-O’Callaghan, Albert, Hanna, Michael G., Machado, Pedro M., Pachman, Lauren M., Reed, Ann M., Rider, Lisa G., Cobb, Joanna, Platt, Hazel, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille, Radstake, Timothy, Doria, Andrea, De Bleecker, Jan, De Paepe, Boel, Maurer, Britta, Ollier, William E., Padyukov, Leonid, O’Hanlon, Terrance P., Lee, Annette, Amos, Christopher I., Gieger, Christian, Meitinger, Thomas, Winkelmann, Juliane, Wedderburn, Lucy R, Chinoy, Hector, Lamb, Janine A
出版年 Ann Rheum Dis (2015)

Immune‐Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA–DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum

著者: Rothwell, Simon, Cooper, Robert G., Lundberg, Ingrid E., Gregersen, Peter K., Hanna, Michael G., Machado, Pedro M., Herbert, Megan K., Pruijn, Ger J. M., Lilleker, James B., Roberts, Mark, Bowes, John, Seldin, Michael F., Vencovsky, Jiri, Danko, Katalin, Limaye, Vidya, Selva‐O'Callaghan, Albert, Platt, Hazel, Molberg, Øyvind, Benveniste, Olivier, Radstake, Timothy R. D. J., Doria, Andrea, De Bleecker, Jan, De Paepe, Boel, Gieger, Christian, Meitinger, Thomas, Winkelmann, Juliane, Amos, Christopher I., Ollier, William E., Padyukov, Leonid, Lee, Annette T., Lamb, Janine A., Chinoy, Hector, Denton, Christopher, Gheorghe, Karina, Hilton‐Jones, David, Kiely, Patrick, Mann, Herman
出版年 Arthritis Rheumatol (2017)

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

著者: Rothwell, Simon, Chinoy, Hector, Lamb, Janine A, Miller, Frederick W, Rider, Lisa G, Wedderburn, Lucy R, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovský, Jiří, Deakin, Claire T, Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M, Reed, Ann M, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille R, Radstake, Timothy R D J, Doria, Andrea, de Bleecker, Jan, Lee, Annette T, Hanna, Michael G, Machado, Pedro M, Ollier, William E, Gregersen, Peter K, Padyukov, Leonid, O'Hanlon, Terrance P, Cooper, Robert G, Lundberg, Ingrid E
出版年 Ann Rheum Dis (2019)