Structural evaluation of EGFR inhibition mechanisms for nanobodies/VHH domains

Por Schmitz, Karl R., Bagchi, Atrish, Roovers, Rob C., van Bergen en Henegouwen, Paul M. P., Ferguson, Kathryn M.
Publicado em 2013

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand-binding

Por Low-Nam, Shalini T., Lidke, Keith A., Cutler, Patrick J., Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Wilson, Bridget S., Lidke, Diane S.
Publicado em 2011

High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display

Por Salema, Valencio, Mañas, Carmen, Cerdán, Lidia, Piñero-Lambea, Carlos, Marín, Elvira, Roovers, Rob C., Van Bergen en Henegouwen, Paul M.P., Fernández, Luis Ángel
Publicado no MAbs (2016)

Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET

Por Vosjan, Maria J. W. D., Perk, Lars R., Roovers, Rob C., Visser, Gerard W. M., Stigter-van Walsum, Marijke, van Bergen en Henegouwen, Paul M. P., van Dongen, Guus A. M. S.
Publicado em 2011

Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects

Por van de Water, Jeroen A. J. M., Bagci-Onder, Tugba, Agarwal, Aayush S., Wakimoto, Hiroaki, Roovers, Rob C., Zhu, Yanni, Kasmieh, Randa, Bhere, Deepak, Van Bergen en Henegouwen, Paul M. P., Shah, Khalid
Publicado em 2012

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform

Por Klarenbeek, Alex, Mazouari, Khalil El, Desmyter, Aline, Blanchetot, Christophe, Hultberg, Anna, de Jonge, Natalie, Roovers, Rob C, Cambillau, Christian, Spinelli, Sylvia, Del-Favero, Jurgen, Verrips, Theo, de Haard, Hans J, Achour, Ikbel
Publicado no MAbs (2015)

Amphiregulin enhances regulatory T cell suppressive function via the epidermal growth factor receptor

Por Zaiss, Dietmar M.W., van Loosdregt, Jorg, Gorlani, Andrea, Bekker, Cornelis P.J., Gröne, Andrea, Sibilia, Maria, van Bergen en Henegouwen, Paul M. P., Roovers, Rob C., Coffer, Paul J., Sijts, Alice J. A. M.
Publicado em 2013

A bi-paratopic anti-EGFR nanobody efficiently inhibits solid tumour growth

Por Roovers, Rob C., Vosjan, Maria J.W.D., Laeremans, Toon, el Khoulati, Rachid, de Bruin, Renée C.G., Ferguson, Kathryn M., Verkleij, Arie J., van Dongen, Guus A.M.S., van Bergen en Henegouwen, Paul M. P.
Publicado em 2011