Epigenetics in human autoimmunity: (Epigenetics in autoimmunity—DNA methylation in systemic lupus erythematosus and beyond)

Por STRICKLAND, FAITH M., RICHARDSON, BRUCE C.
Publicado em 2008

Dissecting complex epigenetic alterations in human lupus

Por Patel, Dipak R, Richardson, Bruce C
Publicado em 2013

Epigenetic mechanisms in lupus

Por Patel, Dipak R., Richardson, Bruce C.
Publicado em 2010

Environmental Exposures, Epigenetic Changes and the Risk of Lupus

Por Somers, Emily C, Richardson, Bruce C
Publicado em 2014

Epigenetics in 2013: DNA methylation and miRNA—key roles in systemic autoimmunity

Por Richardson, Bruce C., Patel, Dipak R.
Publicado no Nat Rev Rheumatol (2014)

PKCδ OXIDATION CONTRIBUTES TO ERK INACTIVATION IN LUPUS T CELLS()

Por Gorelik, Gabriela J., Yarlagadda, Sushma, Richardson, Bruce C.
Publicado em 2012

Decreased ERK and JNK signaling contribute to gene overexpression in “senescent” CD4+CD28– T cells through epigenetic mechanisms

Por Chen, Yingxuan, Gorelik, Gabriela J., Strickland, Faith M., Richardson, Bruce C.
Publicado em 2010

Oxidative Stress, T Cell DNA Methylation, and Lupus

Por Li, YePeng, Gorelik, Gabriela, Strickland, Faith M, Richardson, Bruce C
Publicado em 2014

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis

Por Hewagama, Anura, Patel, Dipak, Yarlagadda, Sushma, Strickland, Faith M., Richardson, Bruce C.
Publicado em 2009

CD4(+) T Cells Epigenetically Modified by Oxidative Stress Cause Lupus-like Autoimmunity in Mice

Por Strickland, Faith M., Li, YePeng, Johnson, Kent, Sun, Zhichao, Richardson, Bruce C.
Publicado no J Autoimmun (2015)

Hypermethylation of PTGER2 Confers Prostaglandin E(2) Resistance in Fibrotic Fibroblasts from Humans and Mice

Por Huang, Steven K., Fisher, Aaron S., Scruggs, Anne M., White, Eric S., Hogaboam, Cory M., Richardson, Bruce C., Peters-Golden, Marc
Publicado em 2010

Prostaglandin E(2) increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression

Por Huang, Steven K., Scruggs, Anne M., Donaghy, Jake, McEachin, Richard C., Fisher, Aaron S., Richardson, Bruce C., Peters-Golden, Marc
Publicado em 2012

Recent Advances and Opportunities in Research on Lupus: Environmental Influences and Mechanisms of Disease

Por Cooper, Glinda S., Gilbert, Kathleen M., Greidinger, Eric L., James, Judith A., Pfau, Jean C., Reinlib, Leslie, Richardson, Bruce C., Rose, Noel R.
Publicado em 2008

Diet Influences Expression of Autoimmune Associated Genes and Disease Severity By Epigenetic Mechanisms in a Transgenic Lupus Model

Por Strickland, Faith M., Hewagama, Anura, Wu, Ailing, Sawalha, Amr H., Delaney, Colin, Hoeltzel, Mark F., Yung, Raymond, Johnson, Kent, Mickelson, Barbara, Richardson, Bruce C.
Publicado em 2013

Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptor Molecules are Expressed and Functional on Lupus T Cells

Por Basu, Dhiman, Liu, Ying, Wu, Ailing, Yarlagadda, Sushma, Gorelik, Gabriela J., Kaplan, Mariana J., Hewagama, Anura, Hinderer, Robert C., Strickland, Faith M., Richardson, Bruce C.
Publicado em 2009

Environmental Exposure, Estrogen and Two X Chromosomes are Required for Disease Development in an Epigenetic Model of Lupus

Por Strickland, Faith M., Hewagama, Anura, Lu, Qianjian, Wu, Ailing, Hinderer, Robert, Webb, Ryan, Johnson, Kent, Sawalha, Amr H., Delaney, Colin, Yung, Raymond, Richardson, Bruce C.
Publicado em 2011

Benzodiazepine-induced superoxide signalsB cell apoptosis: mechanistic insight and potential therapeutic utility

Por Blatt, Neal B., Bednarski, Jeffrey J., Warner, Roscoe E., Leonetti, Francesco, Johnson, Kathryn M., Boitano, Anthony, Yung, Raymond, Richardson, Bruce C., Johnson, Kent J., Ellman, Jonathan A., Opipari, Anthony W., Glick, Gary D.
Publicado em 2002

Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE

Por Kennedy, William P, Maciuca, Romeo, Wolslegel, Kristen, Tew, Wei, Abbas, Alexander R, Chaivorapol, Christina, Morimoto, Alyssa, McBride, Jacqueline M, Brunetta, Paul, Richardson, Bruce C, Davis, John C, Behrens, Timothy W, Townsend, Michael J
Publicado no Lupus Sci Med (2015)

Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients

Por Webb, Ryan, Kelly, Jennifer A, Somers, Emily C, Hughes, Travis, Kaufman, Kenneth M, Sanchez, Elena, Nath, Swapan K, Bruner, Gail, Alarcón-Riquelme, Marta E, Gilkeson, Gary S, Kamen, Diane L, Richardson, Bruce C, Harley, John B, Sawalha, Amr H
Publicado em 2010

Identification of novel genetic susceptibility loci in African-American lupus patients using a candidate gene association study

Por Sanchez, Elena, Comeau, Mary E., Freedman, Barry I., Kelly, Jennifer A., Kaufman, Kenneth M., Langefeld, Carl D., Brown, Elizabeth E., Alarcón, Graciela S., Kimberly, Robert P., Edberg, Jeffrey C., Ramsey-Goldman, Rosalind, Petri, Michelle, Reveille, John D., Vilá, Luis M., Merrill, Joan T., Tsao, Betty P., Kamen, Diane L, Gilkeson, Gary S., James, Judith A., Vyse, Timothy J., Gaffney, Patrick M., Jacob, Chaim O., Niewold, Timothy B., Richardson, Bruce C., Harley, John B., Alarcón-Riquelme, Marta E., Sawalha, Amr H.
Publicado em 2011