Environmental Exposure, Estrogen and Two X Chromosomes are Required for Disease Development in an Epigenetic Model of Lupus

Systemic lupus erythematosus (SLE) is an autoimmune disease primarily afflicting women. The reason for the gender bias is unclear, but genetic susceptibility, estrogen and environmental agents appear to play significant roles in SLE pathogenesis. Environmental agents can contribute to lupus suscepti...

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Detalhes bibliográficos
Main Authors: Strickland, Faith M., Hewagama, Anura, Lu, Qianjian, Wu, Ailing, Hinderer, Robert, Webb, Ryan, Johnson, Kent, Sawalha, Amr H., Delaney, Colin, Yung, Raymond, Richardson, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312994/
https://ncbi.nlm.nih.gov/pubmed/22142890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.11.001
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