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The genetics and epigenetics of autoimmune diseases

Self tolerance loss is fundamental to autoimmunity. While understanding of immune regulation is expanding rapidly, the mechanisms causing loss of tolerance in most autoimmune diseases remain elusive. Autoimmunity is believed to develop when genetically predisposed individuals encounter environmental...

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Detalhes bibliográficos
Main Authors: Hewagama, Anura, Richardson, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819418/
https://ncbi.nlm.nih.gov/pubmed/19349147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.03.007
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