Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptor Molecules are Expressed and Functional on Lupus T Cells

T cells from lupus patients have hypomethylated DNA and overexpress genes normally suppressed by DNA methylation that contribute to disease pathogenesis. We found that stimulatory and inhibitory killer cell immunoglobulin–like receptor (KIR) genes are aberrantly overexpressed on experimentally demet...

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Hauptverfasser: Basu, Dhiman, Liu, Ying, Wu, Ailing, Yarlagadda, Sushma, Gorelik, Gabriela J., Kaplan, Mariana J., Hewagama, Anura, Hinderer, Robert C., Strickland, Faith M., Richardson, Bruce C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730421/
https://ncbi.nlm.nih.gov/pubmed/19675166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900034
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