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Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptor Molecules are Expressed and Functional on Lupus T Cells

T cells from lupus patients have hypomethylated DNA and overexpress genes normally suppressed by DNA methylation that contribute to disease pathogenesis. We found that stimulatory and inhibitory killer cell immunoglobulin–like receptor (KIR) genes are aberrantly overexpressed on experimentally demet...

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Detalhes bibliográficos
Main Authors: Basu, Dhiman, Liu, Ying, Wu, Ailing, Yarlagadda, Sushma, Gorelik, Gabriela J., Kaplan, Mariana J., Hewagama, Anura, Hinderer, Robert C., Strickland, Faith M., Richardson, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730421/
https://ncbi.nlm.nih.gov/pubmed/19675166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900034
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