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Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptor Molecules are Expressed and Functional on Lupus T Cells

T cells from lupus patients have hypomethylated DNA and overexpress genes normally suppressed by DNA methylation that contribute to disease pathogenesis. We found that stimulatory and inhibitory killer cell immunoglobulin–like receptor (KIR) genes are aberrantly overexpressed on experimentally demet...

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書誌詳細
主要な著者: Basu, Dhiman, Liu, Ying, Wu, Ailing, Yarlagadda, Sushma, Gorelik, Gabriela J., Kaplan, Mariana J., Hewagama, Anura, Hinderer, Robert C., Strickland, Faith M., Richardson, Bruce C.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730421/
https://ncbi.nlm.nih.gov/pubmed/19675166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900034
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