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MURINE MODELS OF LUPUS INDUCED BY HYPOMETHYLATED T CELLS
CD4+ T cell DNA hypomethylation may contribute to the development of drug induced and idiopathic human lupus. Inhibiting DNA methylation in mature CD4+ T cells causes MHC-specific autoreactivity in vitro. The lupus-inducing drugs hydralazine and procainamide also inhibit T cell DNA methylation and i...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023250/ https://ncbi.nlm.nih.gov/pubmed/15286391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1385/1-59259-805-6:285 |
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