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CD4(+) T Cells Epigenetically Modified by Oxidative Stress Cause Lupus-like Autoimmunity in Mice

Lupus develops when genetically predisposed people encounter environmental agents such as UV light, silica, infections and cigarette smoke that cause oxidative stress, but how oxidative damage modifies the immune system to cause lupus flares is unknown. We previously showed that oxidizing agents dec...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Strickland, Faith M., Li, YePeng, Johnson, Kent, Sun, Zhichao, Richardson, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529773/
https://ncbi.nlm.nih.gov/pubmed/26165613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.06.004
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