Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

por Monteiro, Rui, Pinheiro, Philip, Joseph, Nicola, Peterkin, Tessa, Koth, Jana, Repapi, Emmanouela, Bonkhofer, Florian, Kirmizitas, Arif, Patient, Roger
Publicado no Dev Cell (2016)

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

por Merryweather-Clarke, Alison T., Cook, David, Lara, Barbara Joo, Hua, Peng, Repapi, Emmanouela, Ashley, Neil, Lim, Shiang Y., Watt, Suzanne M.
Publicado no Stem Cell Res Ther (2018)

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo

por Lukoseviciute, Martyna, Gavriouchkina, Daria, Williams, Ruth M., Hochgreb-Hagele, Tatiana, Senanayake, Upeka, Chong-Morrison, Vanessa, Thongjuea, Supat, Repapi, Emmanouela, Mead, Adam, Sauka-Spengler, Tatjana
Publicado no Dev Cell (2018)

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo

por Williams, Ruth M., Candido-Ferreira, Ivan, Repapi, Emmanouela, Gavriouchkina, Daria, Senanayake, Upeka, Ling, Irving T.C., Telenius, Jelena, Taylor, Stephen, Hughes, Jim, Sauka-Spengler, Tatjana
Publicado no Dev Cell (2019)

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

por Zhang, Yonghong, Makvandi-Nejad, Shokouh, Qin, Ling, Zhao, Yan, Zhang, Tong, Wang, Lili, Repapi, Emmanouela, Taylor, Stephen, McMichael, Andrew, Li, Ning, Dong, Tao, Wu, Hao
Publicado no AIDS (2015)

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation

por Godfrey, Laura, Kerry, Jon, Thorne, Ross, Repapi, Emmanouela, Davies, James O.J., Tapia, Marta, Ballabio, Erica, Hughes, Jim R., Geng, Huimin, Konopleva, Marina, Milne, Thomas A.
Publicado no Exp Hematol (2017)

BET inhibition disrupts transcription but retains enhancer-promoter contact

por Crump, Nicholas T., Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O. J., Milne, Thomas A.
Publicado no Nat Commun (2021)

IL-6 effector function of group-2 innate lymphoid cells (ILC2) is NOD2 dependent

por Hardman, Clare S., Chen, Yi-Ling, Salimi, Maryam, Nahler, Janina, Corridoni, Daniele, Jagielowicz, Marta, Fonseka, Chathuranga L., Johnson, David, Repapi, Emmanouela, Cousins, David J., Barlow, Jillian L., McKenzie, Andrew N. J., Simmons, Alison, Ogg, Graham
Publicado no Sci Immunol (2021)

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

por Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Publicado no Cell Rep (2017)

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

por Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.
Publicado no Nat Commun (2019)

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide

por Ramcharan, Roger, Aleksic, Tamara, Kamdoum, Wilfride Petnga, Gao, Shan, Pfister, Sophia X., Tanner, Jordan, Bridges, Esther, Asher, Ruth, Watson, Amanda J., Margison, Geoffrey P., Woodcock, Mick, Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R., Macaulay, Valentine M.
Publicado no Oncotarget (2015)

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

por Chagraoui, Hedia, Kristiansen, Maiken S., Ruiz, Juan Pablo, Serra-Barros, Ana, Richter, Johanna, Hall-Ponselé, Elisa, Gray, Nicki, Waithe, Dominic, Clark, Kevin, Hublitz, Philip, Repapi, Emmanouela, Otto, Georg, Sopp, Paul, Taylor, Stephen, Thongjuea, Supat, Vyas, Paresh, Porcher, Catherine
Publicado no Nat Commun (2018)

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort

por Zhang, Yong-Hong, Zhao, Yan, Rajapaksa, Ushani S., Lawrence, Tessa M., Peng, Yan-Chun, Liu, Jinghua, Xu, Keyi, Hu, Ke, Qin, Ling, Liu, Ning, Sun, Huanqin, Yan, Hui-Ping, Repapi, Emmanouela, Rowland-Jones, Sarah, Thimme, Robert, McKeating, Jane A., Dong, Tao
Publicado no PLoS One (2016)

Heterogeneity of human lympho-myeloid progenitors at the single cell level

por Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Gottgens, Berthold, Vyas, Paresh
Publicado no Nat Immunol (2017)

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation

por Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A.G., Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M., Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J.
Publicado no Haematologica (2019)

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

por Zeron-Medina, Jorge, Wang, Xuting, Repapi, Emmanouela, Campbell, Michelle R., Su, Dan, Castro-Giner, Francesc, Davies, Benjamin, Peterse, Elisabeth F.P., Sacilotto, Natalia, Walker, Graeme J., Terzian, Tamara, Tomlinson, Ian P., Box, Neil F., Meinshausen, Nicolai, De Val, Sarah, Bell, Douglas A., Bond, Gareth L.
Publicado em 2013

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

por Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Publicado no J Clin Invest (2017)

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

por Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Publicado no J Clin Invest (2017)

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

por Gooding, Sarah, Olechnowicz, Sam W. Z., Morris, Emma V., Armitage, Andrew E., Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R., Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J., Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M.
Publicado no Nat Commun (2019)

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

por Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M. D., Hardman, Clare S., Alham, Nasullah K., Rigby, Rachel E., Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Publicado no Front Immunol (2021)