The Complex Molecular Biology of Amyotrophic Lateral Sclerosis (ALS)

Por Redler, Rachel L., Dokholyan, Nikolay V.
Publicado em 2012

Protein Destabilization as a Common Factor in Diverse Inherited Disorders

Por Redler, Rachel L., Das, Jhuma, Diaz, Juan R., Dokholyan, Nikolay V.
Publicado no J Mol Evol (2015)

Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS)

Por Redler, Rachel L., Fee, Lanette, Fay, James M., Caplow, Michael, Dokholyan, Nikolay V.
Publicado em 2014

Cu,Zn-Superoxide Dismutase without Zn is Folded but Catalytically Inactive

Por Nedd, Sean, Redler, Rachel L., Proctor, Elizabeth A., Dokholyan, Nikolay V., Alexandrova, Anastassia N.
Publicado no J Mol Biol (2014)

Glutathionylation at Cys-111 Induces Dissociation of Wild Type and FALS Mutant SOD1 Dimers

Por Redler, Rachel L., Wilcox, Kyle C., Proctor, Elizabeth A., Fee, Lanette, Caplow, Michael, Dokholyan, Nikolay V.
Publicado em 2011

Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes: A POSSIBLE ROLE IN AMYOTROPHIC LATERAL SCLEROSIS

Por Wilcox, Kyle C., Zhou, Li, Jordon, Joshua K., Huang, Yi, Yu, Yanbao, Redler, Rachel L., Chen, Xian, Caplow, Michael, Dokholyan, Nikolay V.
Publicado em 2009

Serotonin-Induced Hypersensitivity via Inhibition of Catechol O-Methyltransferase Activity

Por Tsao, Douglas, Wieskopf, Jeffrey S, Rashid, Naim, Sorge, Robert E, Redler, Rachel L, Segall, Samantha K, Mogil, Jeffrey S, Maixner, William, Dokholyan, Nikolay V, Diatchenko, Luda
Publicado em 2012

Computational approaches to understanding protein aggregation in neurodegeneration

Por Redler, Rachel L., Shirvanyants, David, Dagliyan, Onur, Ding, Feng, Kim, Doo Nam, Kota, Pradeep, Proctor, Elizabeth A., Ramachandran, Srinivas, Tandon, Arpit, Dokholyan, Nikolay V.
Publicado em 2014

Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis

Por Proctor, Elizabeth A., Fee, Lanette, Tao, Yazhong, Redler, Rachel L., Fay, James M., Zhang, Yuliang, Lv, Zhengjian, Mercer, Ian P., Deshmukh, Mohanish, Lyubchenko, Yuri L., Dokholyan, Nikolay V.
Publicado no Proc Natl Acad Sci U S A (2016)