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Computational approaches to understanding protein aggregation in neurodegeneration
The generation of toxic non-native protein conformers has emerged as a unifying thread among disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Atomic-level detail regarding dynamical changes that facilitate protein aggregation, as well as the st...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995224/ https://ncbi.nlm.nih.gov/pubmed/24620031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mju007 |
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