Protein alkylation by the α,β-unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling?

Por Randall, Matthew J., Hristova, Milena, van der Vliet, Albert
Publicado em 2013

Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1()()

Por Randall, Matthew J., Spiess, Page C., Hristova, Milena, Hondal, Robert J., van der Vliet, Albert
Publicado em 2013

The Tobacco Smoke Component, Acrolein, Suppresses Innate Macrophage Responses by Direct Alkylation of c-Jun N-Terminal Kinase

Por Hristova, Milena, Spiess, Page C., Kasahara, David I., Randall, Matthew J., Deng, Bin, van der Vliet, Albert
Publicado em 2012

The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase

Por Randall, Matthew J., Haenen, Guido R.M.M., Bouwman, Freek G., van der Vliet, Albert, Bast, Aalt
Publicado no Toxicol Lett (2015)

Acrolein exposure suppresses antigen-induced pulmonary inflammation

Por Spiess, Page C, Kasahara, David, Habibovic, Aida, Hristova, Milena, Randall, Matthew J, Poynter, Matthew E, van der Vliet, Albert
Publicado em 2013

Anti-Inflammatory Effects of Levalbuterol-Induced 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Airway Epithelial Cells

Por Randall, Matthew J., Kostin, Shannon F., Burgess, Edward J., Hoyt, Laura R., Ather, Jennifer L., Lundblad, Lennart K., Poynter, Matthew E.
Publicado no Front Endocrinol (Lausanne) (2015)

Inhalation of the Reactive Aldehyde Acrolein Promotes Antigen Sensitization to Ovalbumin and Enhances Neutrophilic Inflammation

Por O’Brien, Edmund, Spiess, Page C., Habibovic, Aida, Hristova, Milena, Bauer, Robert A., Randall, Matthew J., Poynter, Matthew E., van der Vliet, Albert
Publicado no J Immunotoxicol (2015)

Uricase Inhibits Nitrogen Dioxide-Promoted Allergic Sensitization to Inhaled Ovalbumin Independent of Uric Acid Catabolism

Por Ather, Jennifer L., Burgess, Edward J., Hoyt, Laura R., Randall, Matthew J., Mandal, Mridul K., Matthews, Dwight E., Boyson, Jonathan E., Poynter, Matthew E.
Publicado no J Immunol (2016)

Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation

Por Hoyt, Laura R., Ather, Jennifer L., Randall, Matthew J., DePuccio, Daniel P., Landry, Christopher C., Wewers, Mark D., Gavrilin, Mikhail A., Poynter, Matthew E.
Publicado no J Immunol (2016)

Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome()

Por Hoyt, Laura R., Randall, Matthew J., Ather, Jennifer L., DePuccio, Daniel P., Landry, Christopher C., Qian, Xi, Janssen-Heininger, Yvonne M., van der Vliet, Albert, Dixon, Anne E., Amiel, Eyal, Poynter, Matthew E.
Publicado no Redox Biol (2017)

Weight Loss Decreases Inherent and Allergic Methacholine Hyperresponsiveness in Mouse Models of Diet-Induced Obese Asthma

Por Ather, Jennifer L., Chung, Michael, Hoyt, Laura R., Randall, Matthew J., Georgsdottir, Anna, Daphtary, Nirav A., Aliyeva, Minara I., Suratt, Benjamin T., Bates, Jason H. T., Irvin, Charles G., Russell, Sheila R., Forgione, Patrick M., Dixon, Anne E., Poynter, Matthew E.
Publicado no Am J Respir Cell Mol Biol (2016)

Ablation of Glutaredoxin-1 Modulates House Dust Mite–Induced Allergic Airways Disease in Mice

Por Hoffman, Sidra M., Qian, Xi, Nolin, James D., Chapman, David G., Chia, Shi Biao, Lahue, Karolyn G., Schneider, Robert, Ather, Jennifer L., Randall, Matthew J., McMillan, David H., Jones, Jane T., Taatjes, Douglas J., Aliyeva, Minara, Daphtary, Nirav, Abdalla, Sarah, Lundblad, Lennart K. A., Ho, Ye-Shih, Anathy, Vikas, Irvin, Charles G., Wouters, Emiel F. M., Reynaert, Niki L., Dixon, Anne E., van der Vliet, Albert, Poynter, Matthew E., Janssen-Heininger, Yvonne M. W.
Publicado no Am J Respir Cell Mol Biol (2016)