Ablation of Glutaredoxin-1 Modulates House Dust Mite–Induced Allergic Airways Disease in Mice

Protein S-glutathionylation (PSSG) is an oxidant-induced post-translational modification of protein cysteines that impacts structure and function. The oxidoreductase glutaredoxin-1 (Glrx1) under physiological conditions catalyzes deglutathionylation and restores the protein thiol group. The involvem...

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Publicado en:Am J Respir Cell Mol Biol
Main Authors: Hoffman, Sidra M., Qian, Xi, Nolin, James D., Chapman, David G., Chia, Shi Biao, Lahue, Karolyn G., Schneider, Robert, Ather, Jennifer L., Randall, Matthew J., McMillan, David H., Jones, Jane T., Taatjes, Douglas J., Aliyeva, Minara, Daphtary, Nirav, Abdalla, Sarah, Lundblad, Lennart K. A., Ho, Ye-Shih, Anathy, Vikas, Irvin, Charles G., Wouters, Emiel F. M., Reynaert, Niki L., Dixon, Anne E., van der Vliet, Albert, Poynter, Matthew E., Janssen-Heininger, Yvonne M. W.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2016
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023028/
https://ncbi.nlm.nih.gov/pubmed/27035878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0401OC
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