Epithelial Nuclear Factor- kappa B orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling

NF-κB activation within the epithelium has been implicated in the pathogenesis of asthma, yet the exact role of epithelial NF-κB in allergen-induced inflammation and airway remodeling remains unclear. In the present study, we utilized an intranasal House Dust Mite (HDM) extract exposure regimen time...

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Detalhes bibliográficos
Main Authors: Tully, Jane E., Hoffman, Sidra M., Lahue, Karolyn G., Nolin, James D., Anathy, Vikas, Lundblad, Lennart K. A., Daphtary, Nirav, Aliyeva, Minara, Black, Kendall E., Dixon, Anne E., Poynter, Matthew E., Irvin, Charles G., Janssen-Heininger, Yvonne M. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858534/
https://ncbi.nlm.nih.gov/pubmed/24227776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301329
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