Weight Loss Decreases Inherent and Allergic Methacholine Hyperresponsiveness in Mouse Models of Diet-Induced Obese Asthma

Obese asthma presents with inherent hyperresponsiveness to methacholine or augmented allergen-driven allergic asthma, with an even greater magnitude of methacholine hyperresponsiveness. These physiologic parameters and accompanying obese asthma symptoms can be reduced by successful weight loss, yet...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Ather, Jennifer L., Chung, Michael, Hoyt, Laura R., Randall, Matthew J., Georgsdottir, Anna, Daphtary, Nirav A., Aliyeva, Minara I., Suratt, Benjamin T., Bates, Jason H. T., Irvin, Charles G., Russell, Sheila R., Forgione, Patrick M., Dixon, Anne E., Poynter, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979374/
https://ncbi.nlm.nih.gov/pubmed/27064658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0070OC
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