Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome()

Alcohol use disorders are common both in the United States and globally, and are associated with a variety of co-morbid, inflammation-linked diseases. The pathogenesis of many of these ailments are driven by the activation of the NLRP3 inflammasome, a multi-protein intracellular pattern recognition...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Hoyt, Laura R., Randall, Matthew J., Ather, Jennifer L., DePuccio, Daniel P., Landry, Christopher C., Qian, Xi, Janssen-Heininger, Yvonne M., van der Vliet, Albert, Dixon, Anne E., Amiel, Eyal, Poynter, Matthew E.
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413213/
https://ncbi.nlm.nih.gov/pubmed/28463821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.020
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