Targeting tumor-associated macrophages in cancer therapy and understanding their complexity

di Cannarile, Michael A., Ries, Carola H., Hoves, Sabine, Rüttinger, Dominik
Pubblicato in Oncoimmunology (2014)

Concentrations of EpCAM ectodomain as found in sera of cancer patients do not significantly impact redirected lysis and T-cell activation by EpCAM/CD3-bispecific BiTE antibody MT11...

di Petsch, Silke, Gires, Olivier, Rüttinger, Dominik, Denzel, Sabine, Lippold, Sandra, Baeuerle, Patrick A, Wolf, Andreas
Pubblicazione 2011

Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

di Cannarile, Michael A., Weisser, Martin, Jacob, Wolfgang, Jegg, Anna-Maria, Ries, Carola H., Rüttinger, Dominik
Pubblicato in J Immunother Cancer (2017)

Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer

di van den Engel, Natasja K, Rüttinger, Dominik, Rusan, Margareta, Kammerer, Robert, Zimmermann, Wolfgang, Hatz, Rudolf A, Winter, Hauke
Pubblicazione 2011

Immunotherapy of Cancer: Key Findings and Commentary on the Third Tegernsee Conference

di Rüttinger, Dominik, Winter, Hauke, van den Engel, Natasja K., Hatz, Rudolf, Jauch, Karl-Walter, Fox, Bernard A., Weber, Jeffrey S.
Pubblicazione 2010

PK/PD Mediated Dose Optimization of Emactuzumab, a CSF1R Inhibitor, in Patients With Advanced Solid Tumors and Diffuse‐Type Tenosynovial Giant Cell Tumor

di Smart, Kevin, Bröske, Ann‐Marie, Rüttinger, Dominik, Mueller, Claudia, Phipps, Alex, Walz, Antje‐Christine, Ries, Carola, Baehner, Monika, Cannarile, Michael, Meneses‐Lorente, Georgina
Pubblicato in Clin Pharmacol Ther (2020)

Highly Efficient Elimination of Colorectal Tumor-Initiating Cells by an EpCAM/CD3-Bispecific Antibody Engaging Human T Cells

di Herrmann, Ines, Baeuerle, Patrick A., Friedrich, Matthias, Murr, Alexander, Filusch, Susanne, Rüttinger, Dominik, Majdoub, Mariam W., Sharma, Sherven, Kufer, Peter, Raum, Tobias, Münz, Markus
Pubblicazione 2010

High-grade, chemotherapy-resistant ovarian carcinomas overexpress epithelial cell adhesion molecule (EpCAM) and are highly sensitive to immunotherapy with MT201, a fully human mono...

di Richter, Christine E., Cocco, Emiliano, Bellone, Stefania, Silasi, Dan-Arin, Rüttinger, Dominik, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.
Pubblicazione 2010

Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an i...

di Rüttinger, Dominik, van den Engel, Natasja K, Winter, Hauke, Schlemmer, Marcus, Pohla, Heike, Grützner, Stefanie, Wagner, Beate, Schendel, Dolores J, Fox, Bernard A, Jauch, K-W, Hatz, Rudolf A
Pubblicazione 2007

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

di Münz, Markus, Murr, Alexander, Kvesic, Majk, Rau, Doris, Mangold, Susanne, Pflanz, Stefan, Lumsden, John, Volkland, Jörg, Fagerberg, Jan, Riethmüller, Gert, Rüttinger, Dominik, Kufer, Peter, Baeuerle, Patrick A, Raum, Tobias
Pubblicazione 2010

Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines

di Winter, Hauke, van den Engel, Natasja K, Rüttinger, Dominik, Schmidt, Jürgen, Schiller, Matthias, Poehlein, Christian H, Löhe, Florian, Fox, Bernard A, Jauch, Karl-Walter, Hatz, Rudolf A, Hu, Hong-Ming
Pubblicazione 2007

Active-specific immunotherapy for non-small cell lung cancer

di Winter, Hauke, van den Engel, Natasja K., Rusan, Margareta, Schupp, Nina, Poehlein, Christian H., Hu, Hong-Ming, Hatz, Rudolf A., Urba, Walter J., Jauch, Karl-Walter, Fox, Bernard A., Rüttinger, Dominik
Pubblicazione 2011

Primary Cervical Carcinoma Cell Lines Overexpress Epithelial Cell Adhesion Molecule (EpCAM) and Are Highly Sensitive to Immunotherapy With MT201, a Fully Human Monoclonal Anti-EpCA...

di Richter, Christine E., Cocco, Emiliano, Bellone, Stefania, Bellone, Marta, Casagrande, Francesca, Todeschini, Paola, Rüttinger, Dominik, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.
Pubblicazione 2010

Overexpression of EpCAM in Uterine Serous Papillary Carcinoma: Implications for EpCAM-specific Immunotherapy with Human Monoclonal Antibody Adecatumumab (MT201)

di El-Sahwi, Karim, Bellone, Stefania, Cocco, Emiliano, Casagrande, Francesca, Bellone, Marta, Abu-Khalaf, Maysa, Buza, Natalia, Tavassoli, Fattaneh A., Hui, Pei, Rüttinger, Dominik, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.
Pubblicazione 2010

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

di Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M., Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A., Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H.
Pubblicato in J Exp Med (2018)

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response

di Salvagno, Camilla, Ciampricotti, Metamia, Tuit, Sander, Hau, Cheei-Sing, van Weverwijk, Antoinette, Coffelt, Seth B., Kersten, Kelly, Vrijland, Kim, Kos, Kevin, Ulas, Thomas, Song, Ji-Ying, Ooi, Chia-Huey, Rüttinger, Dominik, Cassier, Philippe A., Jonkers, Jos, Schultze, Joachim L., Ries, Carola H., de Visser, Karin E.
Pubblicato in Nat Cell Biol (2019)

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

di Menke-van der Houven van Oordt, C. Willemien, Gomez-Roca, Carlos, van Herpen, Carla, Coveler, Andrew L., Mahalingam, Devalingam, Verheul, Henk M. W., van der Graaf, Winette T. A., Christen, Randolph, Rüttinger, Dominik, Weigand, Stefan, Cannarile, Michael A., Heil, Florian, Brewster, Michael, Walz, Antje-Christine, Nayak, Tapan K., Guarin, Ernesto, Meresse, Valerie, Le Tourneau, Christophe
Pubblicato in Oncotarget (2016)

Phase Ib study of anti-CSF-1R antibody emactuzumab in combination with CD40 agonist selicrelumab in advanced solid tumor patients

di Machiels, Jean-Pascal, Gomez-Roca, Carlos, Michot, Jean-Marie, Zamarin, Dmitriy, Mitchell, Tara, Catala, Gaetan, Eberst, Lauriane, Jacob, Wolfgang, Jegg, Anna-Maria, Cannarile, Michael A, Watson, Carl, Babitzki, Galina, Korski, Konstanty, Klaman, Irina, Teixeira, Priscila, Hoves, Sabine, Ries, Carola, Meneses-Lorente, Georgina, Michielin, Francesca, Christen, Randolph, Rüttinger, Dominik, Weisser, Martin, Delord, Jean-Pierre, Cassier, Philippe
Pubblicato in J Immunother Cancer (2020)