The Elementary Mass Action Rate Constants of P-gp Transport for a Confluent Monolayer of MDCKII-hMDR1 Cells

door Tran, Thuy Thanh, Mittal, Aditya, Aldinger, Tanya, Polli, Joseph W., Ayrton, Andrew, Ellens, Harma, Bentz, Joe
Gepubliceerd in 2005

Use of Cassette Dosing in Sandwich-Cultured Rat and Human Hepatocytes to Identify Drugs that Inhibit Bile Acid Transport

door Wolf, Kristina K., Vora, Sapana, Webster, Lindsey O., Generaux, Grant T., Polli, Joseph W., Brouwer, Kim L. R.
Gepubliceerd in 2009

Safety, pharmacokinetics and pharmacodynamics of remogliflozin etabonate, a novel SGLT2 inhibitor, and metformin when co-administered in subjects with type 2 diabetes mellitus

door Hussey, Elizabeth K, Kapur, Anita, O’Connor-Semmes, Robin, Tao, Wenli, Rafferty, Bryan, Polli, Joseph W, James, Charles D, Dobbins, Robert L
Gepubliceerd in 2013

Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds

door Murad, Neha, Pasikanti, Kishore K., Madej, Benjamin D., Minnich, Amanda, McComas, Juliet M., Crouch, Sabrinia, Polli, Joseph W., Weber, Andrew D.
Gepubliceerd in Drug Metab Dispos (2021)

The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects

door Adkison, Kimberly K, Vaidya, Soniya S, Lee, Daniel Y, Koo, Seok Hwee, Li, Linghui, Mehta, Amer A, Gross, Annette S, Polli, Joseph W, Lou, Yu, Lee, Edmund J D
Gepubliceerd in 2008

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper from the International Transporter Consortium

door Evers, Raymond, Piquette-Miller, Micheline, Polli, Joseph W., Russel, Frans G. M., Sprowl, Jason A., Tohyama, Kimio, Ware, Joseph A., de Wildt, Saskia N., Xie, Wen, Brouwer, Kim L. R.
Gepubliceerd in Clin Pharmacol Ther (2018)

First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 d...

door Kapur, Anita, O’Connor-Semmes, Robin, Hussey, Elizabeth K, Dobbins, Robert L, Tao, Wenli, Hompesch, Marcus, Smith, Glenn A, Polli, Joseph W, James Jr, Charles D, Mikoshiba, Imao, Nunez, Derek J
Gepubliceerd in 2013

Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

door Taskar, Kunal S., Rudraraju, Vinay, Mittapalli, Rajendar K., Samala, Ramakrishna, R. Thorsheim, Helen, Lockman, Julie, Gril, Brunilde, Hua, Emily, Palmieri, Diane, Polli, Joseph W., Castellino, Stephen, Rubin, Stephen D., Lockman, Paul R., Steeg, Patricia S., Smith, Quentin R.
Gepubliceerd in 2011

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

door Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.
Gepubliceerd in Clin Pharmacol Ther (2018)

Exploring predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis

door Cutrell, Amy G., Schapiro, Jonathan M., Perno, Carlo F., Kuritzkes, Daniel R., Quercia, Romina, Patel, Parul, Polli, Joseph W., Dorey, David, Wang, Yongwei, Wu, Sterling, Van Eygen, Veerle, Crauwels, Herta, Ford, Susan L., Baker, Mark, Talarico, Christine L., Clair, Marty St, Jeffrey, Jerry, White, C. Thomas, Vanveggel, Simon, Vandermeulen, Kati, Margolis, David A., Aboud, Michael, Spreen, William R., van Lunzen, Jan
Gepubliceerd in AIDS (2021)