The Elementary Mass Action Rate Constants of P-gp Transport for a Confluent Monolayer of MDCKII-hMDR1 Cells

Por Tran, Thuy Thanh, Mittal, Aditya, Aldinger, Tanya, Polli, Joseph W., Ayrton, Andrew, Ellens, Harma, Bentz, Joe
Publicado em 2005

Use of Cassette Dosing in Sandwich-Cultured Rat and Human Hepatocytes to Identify Drugs that Inhibit Bile Acid Transport

Por Wolf, Kristina K., Vora, Sapana, Webster, Lindsey O., Generaux, Grant T., Polli, Joseph W., Brouwer, Kim L. R.
Publicado em 2009

Safety, pharmacokinetics and pharmacodynamics of remogliflozin etabonate, a novel SGLT2 inhibitor, and metformin when co-administered in subjects with type 2 diabetes mellitus

Por Hussey, Elizabeth K, Kapur, Anita, O’Connor-Semmes, Robin, Tao, Wenli, Rafferty, Bryan, Polli, Joseph W, James, Charles D, Dobbins, Robert L
Publicado em 2013

Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds

Por Murad, Neha, Pasikanti, Kishore K., Madej, Benjamin D., Minnich, Amanda, McComas, Juliet M., Crouch, Sabrinia, Polli, Joseph W., Weber, Andrew D.
Publicado no Drug Metab Dispos (2021)

The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects

Por Adkison, Kimberly K, Vaidya, Soniya S, Lee, Daniel Y, Koo, Seok Hwee, Li, Linghui, Mehta, Amer A, Gross, Annette S, Polli, Joseph W, Lou, Yu, Lee, Edmund J D
Publicado em 2008

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper from the International Transporter Consortium

Por Evers, Raymond, Piquette-Miller, Micheline, Polli, Joseph W., Russel, Frans G. M., Sprowl, Jason A., Tohyama, Kimio, Ware, Joseph A., de Wildt, Saskia N., Xie, Wen, Brouwer, Kim L. R.
Publicado no Clin Pharmacol Ther (2018)

First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 d...

Por Kapur, Anita, O’Connor-Semmes, Robin, Hussey, Elizabeth K, Dobbins, Robert L, Tao, Wenli, Hompesch, Marcus, Smith, Glenn A, Polli, Joseph W, James Jr, Charles D, Mikoshiba, Imao, Nunez, Derek J
Publicado em 2013

Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

Por Taskar, Kunal S., Rudraraju, Vinay, Mittapalli, Rajendar K., Samala, Ramakrishna, R. Thorsheim, Helen, Lockman, Julie, Gril, Brunilde, Hua, Emily, Palmieri, Diane, Polli, Joseph W., Castellino, Stephen, Rubin, Stephen D., Lockman, Paul R., Steeg, Patricia S., Smith, Quentin R.
Publicado em 2011

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Por Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.
Publicado no Clin Pharmacol Ther (2018)