The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects

AIMS: A number of drugs are substrates or inhibitors of the efflux transporter breast cancer resistance protein (BCRP; ABCG2), which can limit systemic exposure by reducing absorption and/or increasing biliary elimination. The identification of a BCRP-selective clinical probe drug would provide a us...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Adkison, Kimberly K, Vaidya, Soniya S, Lee, Daniel Y, Koo, Seok Hwee, Li, Linghui, Mehta, Amer A, Gross, Annette S, Polli, Joseph W, Lou, Yu, Lee, Edmund J D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492914/
https://ncbi.nlm.nih.gov/pubmed/18429968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03184.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados