Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype

BACKGROUND: Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor that acts against receptors for vascular endothelial growth factor and platelet-derived growth factor. Common toxicities of sunitinib treatment include hypertension, hand–foot syndrome, vomiting, and diarrhea, and the propo...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Miura, Yuji, Imamura, Chiyo K, Fukunaga, Koya, Katsuyama, Yoshihiko, Suyama, Koichi, Okaneya, Toshikazu, Mushiroda, Taisei, Ando, Yuichi, Takano, Toshimi, Tanigawara, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301945/
https://ncbi.nlm.nih.gov/pubmed/25515134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-964
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