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ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population

BACKGROUND: To investigate the associations between atorvastatin-induced liver injury (AILI) and polymorphisms in eight genes possibly involved in the hepatic metabolism (CYP2C9, CYP2C19, CYP3A4, CYP3A5 and UGT1A1) and membrane transport (ABCB1, ABCG2 and SLCO1B1) of atorvastatin, we genotyped 30 AI...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Fukunaga, Koya, Nakagawa, Hiroshi, Ishikawa, Toshihisa, Kubo, Michiaki, Mushiroda, Taisei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906899/
https://ncbi.nlm.nih.gov/pubmed/27296832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0390-5
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