Haplotypes with Copy Number and Single Nucleotide Polymorphisms in CYP2A6 Locus Are Associated with Smoking Quantity in a Japanese Population

Smoking is a major public health problem, but the genetic factors associated with smoking behaviors are not fully elucidated. Here, we have conducted an integrated genome-wide association study to identify common copy number polymorphisms (CNPs) and single nucleotide polymorphisms (SNPs) associated...

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Detalhes bibliográficos
Main Authors: Kumasaka, Natsuhiko, Aoki, Masayuki, Okada, Yukinori, Takahashi, Atsushi, Ozaki, Kouichi, Mushiroda, Taisei, Hirota, Tomomitsu, Tamari, Mayumi, Tanaka, Toshihiro, Nakamura, Yusuke, Kamatani, Naoyuki, Kubo, Michiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458030/
https://ncbi.nlm.nih.gov/pubmed/23049750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044507
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