Association Test Algorithm Between a Qualitative Phenotype and a Haplotype or Haplotype Set Using Simultaneous Estimation of Haplotype Frequencies, Diplotype Configurations and Diplotype-Based Penetrances

Analysis of the association between haplotypes and phenotypes is becoming increasingly important. We have devised an expectation-maximization (EM)-based algorithm to test the association between a phenotype and a haplotype or a haplotype set and to estimate diplotype-based penetrance using individua...

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Main Authors: Ito, Toshikazu, Inoue, Eisuke, Kamatani, Naoyuki
פורמט: Artigo
שפה:Inglês
יצא לאור: Genetics Society of America 2004
נושאים:
Investigations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448736/
https://ncbi.nlm.nih.gov/pubmed/15611197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.024653
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