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Haplotype-aware diplotyping from noisy long reads

Current genotyping approaches for single-nucleotide variations rely on short, accurate reads from second-generation sequencing devices. Presently, third-generation sequencing platforms are rapidly becoming more widespread, yet approaches for leveraging their long but error-prone reads for genotyping...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Ebler, Jana, Haukness, Marina, Pesout, Trevor, Marschall, Tobias, Paten, Benedict
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547545/
https://ncbi.nlm.nih.gov/pubmed/31159868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1709-0
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