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Haplotype-aware graph indexes
MOTIVATION: The variation graph toolkit (VG) represents genetic variation as a graph. Although each path in the graph is a potential haplotype, most paths are non-biological, unlikely recombinations of true haplotypes. RESULTS: We augment the VG model with haplotype information to identify which pat...
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| Pubblicato in: | Bioinformatics |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7223266/ https://ncbi.nlm.nih.gov/pubmed/31406990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz575 |
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