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Variation graph toolkit improves read mapping by representing genetic variation in the reference
Reference genomes guide our interpretation of DNA sequence data. However, conventional linear references represent only one version of each locus, ignoring variation in the population. Poor representation of an individual’s genome sequence impacts read mapping and introduces bias. Variation graphs a...
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| Publicado no: | Nat Biotechnol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6126949/ https://ncbi.nlm.nih.gov/pubmed/30125266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4227 |
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