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A haplotype-aware de novo assembly of related individuals using pedigree sequence graph
MOTIVATION: Reconstructing high-quality haplotype-resolved assemblies for related individuals has important applications in Mendelian diseases and population genomics. Through major genomics sequencing efforts such as the Personal Genome Project, the Vertebrate Genome Project (VGP) and the Genome in...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7759745/ https://ncbi.nlm.nih.gov/pubmed/31860070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz942 |
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