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CHOP: haplotype-aware path indexing in population graphs

The practical use of graph-based reference genomes depends on the ability to align reads to them. Performing substring queries to paths through these graphs lies at the core of this task. The combination of increasing pattern length and encoded variations inevitably leads to a combinatorial explosio...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Mokveld, Tom, Linthorst, Jasper, Al-Ars, Zaid, Holstege, Henne, Reinders, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066762/
https://ncbi.nlm.nih.gov/pubmed/32160922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01963-y
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