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GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller

BACKGROUND: Pairwise sequence alignment is widely used in many biological tools and applications. Existing GPU accelerated implementations mainly focus on calculating optimal alignment score and omit identifying the optimal alignment itself. In GATK HaplotypeCaller (HC), the semi-global pairwise seq...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Ren, Shanshan, Ahmed, Nauman, Bertels, Koen, Al-Ars, Zaid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456962/
https://ncbi.nlm.nih.gov/pubmed/30967111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5468-9
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