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GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller

BACKGROUND: Pairwise sequence alignment is widely used in many biological tools and applications. Existing GPU accelerated implementations mainly focus on calculating optimal alignment score and omit identifying the optimal alignment itself. In GATK HaplotypeCaller (HC), the semi-global pairwise seq...

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Detalles Bibliográficos
Publicado en:BMC Genomics
Main Authors: Ren, Shanshan, Ahmed, Nauman, Bertels, Koen, Al-Ars, Zaid
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456962/
https://ncbi.nlm.nih.gov/pubmed/30967111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5468-9
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