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Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total exe...

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Detalles Bibliográficos
Autores principales: Shanshan Ren, Koen Bertels, Zaid Al-Ars
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publishing 2018-03-01
Colección:Evolutionary Bioinformatics
Acceso en línea:https://doi.org/10.1177/1176934318760543
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