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Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total exe...

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Bibliografiska uppgifter
Huvudupphovsmän: Shanshan Ren, Koen Bertels, Zaid Al-Ars
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publishing 2018-03-01
Serie:Evolutionary Bioinformatics
Länkar:https://doi.org/10.1177/1176934318760543
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