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ADS-HCSpark: A scalable HaplotypeCaller leveraging adaptive data segmentation to accelerate variant calling on Spark

BACKGROUND: The advance of next generation sequencing enables higher throughput with lower price, and as the basic of high-throughput sequencing data analysis, variant calling is widely used in disease research, clinical treatment and medicine research. However, current mainstream variant caller too...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Xiao, Anghong, Wu, Zongze, Dong, Shoubin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376756/
https://ncbi.nlm.nih.gov/pubmed/30764760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2665-0
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