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DECA: scalable XHMM exome copy-number variant calling with ADAM and Apache Spark
BACKGROUND: XHMM is a widely used tool for copy-number variant (CNV) discovery from whole exome sequencing data but can require hours to days to run for large cohorts. A more scalable implementation would reduce the need for specialized computational resources and enable increased exploration of the...
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| Publicado no: | BMC Bioinformatics |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6787990/ https://ncbi.nlm.nih.gov/pubmed/31604420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3108-7 |
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