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DECA: scalable XHMM exome copy-number variant calling with ADAM and Apache Spark
Abstract Background XHMM is a widely used tool for copy-number variant (CNV) discovery from whole exome sequencing data but can require hours to days to run for large cohorts. A more scalable implementation would reduce the need for specialized computational resources and enable increased exploratio...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2019-10-01
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Colecção: | BMC Bioinformatics |
Assuntos: | |
Acesso em linha: | http://link.springer.com/article/10.1186/s12859-019-3108-7 |
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