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Using Apache Spark on genome assembly for scalable overlap-graph reduction

BACKGROUND: De novo genome assembly is a technique that builds the genome of a specimen using overlaps of genomic fragments without additional work with reference sequence. Sequence fragments (called reads) are assembled as contigs and scaffolds by the overlaps. The quality of the de novo assembly d...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genomics
Hauptverfasser: Paul, Alexander J., Lawrence, Dylan, Song, Myoungkyu, Lim, Seung-Hwan, Pan, Chongle, Ahn, Tae-Hyuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805285/
https://ncbi.nlm.nih.gov/pubmed/31639049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0227-1
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