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Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total exe...

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Detalhes bibliográficos
Publicado no:Evol Bioinform Online
Main Authors: Ren, Shanshan, Bertels, Koen, Al-Ars, Zaid
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858735/
https://ncbi.nlm.nih.gov/pubmed/29568218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176934318760543
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