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Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total exe...

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Bibliografiske detaljer
Udgivet i:Evol Bioinform Online
Main Authors: Ren, Shanshan, Bertels, Koen, Al-Ars, Zaid
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858735/
https://ncbi.nlm.nih.gov/pubmed/29568218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176934318760543
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