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CHOP: haplotype-aware path indexing in population graphs

The practical use of graph-based reference genomes depends on the ability to align reads to them. Performing substring queries to paths through these graphs lies at the core of this task. The combination of increasing pattern length and encoded variations inevitably leads to a combinatorial explosio...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Mokveld, Tom, Linthorst, Jasper, Al-Ars, Zaid, Holstege, Henne, Reinders, Marcel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066762/
https://ncbi.nlm.nih.gov/pubmed/32160922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01963-y
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