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Haplotype-aware diplotyping from noisy long reads

Current genotyping approaches for single-nucleotide variations rely on short, accurate reads from second-generation sequencing devices. Presently, third-generation sequencing platforms are rapidly becoming more widespread, yet approaches for leveraging their long but error-prone reads for genotyping...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Ebler, Jana, Haukness, Marina, Pesout, Trevor, Marschall, Tobias, Paten, Benedict
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547545/
https://ncbi.nlm.nih.gov/pubmed/31159868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1709-0
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