Haplotype threading: accurate polyploid phasing from long reads

Resolving genomes at haplotype level is crucial for understanding the evolutionary history of polyploid species and for designing advanced breeding strategies. Polyploid phasing still presents considerable challenges, especially in regions of collapsing haplotypes.We present WhatsHap polyphase, a no...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Schrinner, Sven D., Mari, Rebecca Serra, Ebler, Jana, Rautiainen, Mikko, Seillier, Lancelot, Reimer, Julia J., Usadel, Björn, Marschall, Tobias, Klau, Gunnar W.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504856/
https://ncbi.nlm.nih.gov/pubmed/32951599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02158-1
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