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ParaHaplo 2.0: a program package for haplotype-estimation and haplotype-based whole-genome association study using parallel computing

BACKGROUND: The use of haplotype-based association tests can improve the power of genome-wide association studies. Since the observed genotypes are unordered pairs of alleles, haplotype phase must be inferred. However, estimating haplotype phase is time consuming. When millions of single-nucleotide...

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Autors principals: Misawa, Kazuharu, Kamatani, Naoyuki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892495/
https://ncbi.nlm.nih.gov/pubmed/20525312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1751-0473-5-5
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