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ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population
BACKGROUND: To investigate the associations between atorvastatin-induced liver injury (AILI) and polymorphisms in eight genes possibly involved in the hepatic metabolism (CYP2C9, CYP2C19, CYP3A4, CYP3A5 and UGT1A1) and membrane transport (ABCB1, ABCG2 and SLCO1B1) of atorvastatin, we genotyped 30 AI...
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| Published in: | BMC Genet |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906899/ https://ncbi.nlm.nih.gov/pubmed/27296832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0390-5 |
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