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ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population

BACKGROUND: To investigate the associations between atorvastatin-induced liver injury (AILI) and polymorphisms in eight genes possibly involved in the hepatic metabolism (CYP2C9, CYP2C19, CYP3A4, CYP3A5 and UGT1A1) and membrane transport (ABCB1, ABCG2 and SLCO1B1) of atorvastatin, we genotyped 30 AI...

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Bibliografische gegevens
Gepubliceerd in:BMC Genet
Hoofdauteurs: Fukunaga, Koya, Nakagawa, Hiroshi, Ishikawa, Toshihisa, Kubo, Michiaki, Mushiroda, Taisei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906899/
https://ncbi.nlm.nih.gov/pubmed/27296832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0390-5
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